Item Type | Name |
Concept
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Analysis of Variance
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Concept
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Cell Nucleus
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Concept
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DNA Mutational Analysis
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Concept
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Regression Analysis
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Concept
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Cluster Analysis
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Concept
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Principal Component Analysis
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Concept
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Sequence Analysis, DNA
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Concept
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Solitary Nucleus
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Concept
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Microarray Analysis
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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Active Transport, Cell Nucleus
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Concept
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Multivariate Analysis
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Concept
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Survival Analysis
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Concept
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Meta-Analysis as Topic
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Concept
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Mendelian Randomization Analysis
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Concept
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Tissue Array Analysis
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Concept
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Blood Chemical Analysis
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Concept
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Sequence Analysis, RNA
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Protein Array Analysis
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
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Academic Article
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An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.
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Academic Article
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Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
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Academic Article
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Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
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Academic Article
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Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
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Academic Article
|
Ring finger protein 43 as a new target for cancer immunotherapy.
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Academic Article
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Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
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Academic Article
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Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
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Academic Article
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Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
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Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.
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Academic Article
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A SNP in the ABCC11 gene is the determinant of human earwax type.
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Academic Article
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Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
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Academic Article
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Genome-wide detection and characterization of positive selection in human populations.
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Academic Article
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Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
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Academic Article
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Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
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Academic Article
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Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
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Academic Article
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Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
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Academic Article
|
Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
|
Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
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Academic Article
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Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
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Academic Article
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A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
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Academic Article
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A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
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Academic Article
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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
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Academic Article
|
Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
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Academic Article
|
Criterion values for multiplex SNP genotyping by the invader assay.
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Academic Article
|
Automated SNPs typing system based on the Invader assay.
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Academic Article
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Making a haplotype catalog with estimated frequencies based on SNP homozygotes.
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Academic Article
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Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
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Academic Article
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Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
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Academic Article
|
Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
|
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
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Academic Article
|
Genome-wide association study of intracranial aneurysm identifies three new risk loci.
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Academic Article
|
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
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Academic Article
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Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
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Academic Article
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PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
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Academic Article
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Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
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Academic Article
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Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
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Academic Article
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A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
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Academic Article
|
Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.
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Academic Article
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Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
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Academic Article
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Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
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Academic Article
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A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
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Academic Article
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Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
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Academic Article
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Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
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Academic Article
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Common variation in GPC5 is associated with acquired nephrotic syndrome.
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Academic Article
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Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
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Academic Article
|
Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
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Academic Article
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A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
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Academic Article
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SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
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Academic Article
|
Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
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Academic Article
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Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
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Academic Article
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Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
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Academic Article
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Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
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Academic Article
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A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
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Academic Article
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Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
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Academic Article
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Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
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Academic Article
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Genome-wide association meta-analysis identifies new endometriosis risk loci.
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Academic Article
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Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
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Academic Article
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A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
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Academic Article
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Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
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Academic Article
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Evaluating genetic risk for prostate cancer among Japanese and Latinos.
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Academic Article
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Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
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Academic Article
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A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
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Academic Article
|
A genome-wide association study identifies three new risk loci for Kawasaki disease.
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Academic Article
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Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
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Academic Article
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SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
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Academic Article
|
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
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Academic Article
|
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
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Academic Article
|
Multiple loci are associated with white blood cell phenotypes.
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Academic Article
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Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
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Academic Article
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Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
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Academic Article
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New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
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Academic Article
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A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
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Academic Article
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A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
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Academic Article
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Meta-analysis identifies common variants associated with body mass index in east Asians.
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Academic Article
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A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
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Academic Article
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A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
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Academic Article
|
Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
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Academic Article
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A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
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Academic Article
|
Optineurin mutations in Japanese amyotrophic lateral sclerosis.
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Academic Article
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Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
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Academic Article
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Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
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Academic Article
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Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
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Academic Article
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PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
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Academic Article
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A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
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Academic Article
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A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
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Academic Article
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Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
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Academic Article
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Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
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Academic Article
|
Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
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Academic Article
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Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.
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Academic Article
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A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
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Academic Article
|
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
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Academic Article
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Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
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Academic Article
|
Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
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Academic Article
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Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
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Academic Article
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Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
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Academic Article
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CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.
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Academic Article
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Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
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Academic Article
|
Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
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Academic Article
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A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.
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Academic Article
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Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
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Academic Article
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Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
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Academic Article
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High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
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Academic Article
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A second generation human haplotype map of over 3.1 million SNPs.
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Academic Article
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Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
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Academic Article
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SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
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Academic Article
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CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
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Academic Article
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Genome-wide association study of hematological and biochemical traits in a Japanese population.
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Academic Article
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A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
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Academic Article
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Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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Genome-wide association study of pancreatic cancer in Japanese population.
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Academic Article
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IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
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Academic Article
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Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
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Academic Article
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Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
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Academic Article
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Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
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Academic Article
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Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
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Academic Article
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ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
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Academic Article
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Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
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Academic Article
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Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
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Academic Article
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Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
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Academic Article
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A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
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Academic Article
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Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
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Academic Article
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Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
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Academic Article
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Development of new HLA-B*3505 genotyping method using Invader assay.
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Academic Article
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Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
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Academic Article
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A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
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Academic Article
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A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
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Academic Article
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Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
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Academic Article
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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
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Academic Article
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Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
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Academic Article
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A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
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Academic Article
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A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
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Academic Article
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Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
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Academic Article
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Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
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Academic Article
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Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
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Academic Article
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Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
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Academic Article
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Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
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Academic Article
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Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
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Academic Article
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Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
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Academic Article
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Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
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Academic Article
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Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
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Academic Article
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Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
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Academic Article
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Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
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Academic Article
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Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
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Academic Article
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Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
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Academic Article
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Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
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Academic Article
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Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
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Academic Article
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Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
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Academic Article
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Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.
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Academic Article
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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
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Academic Article
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
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Academic Article
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Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
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Academic Article
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Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
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Academic Article
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Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.
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Academic Article
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Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
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Academic Article
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Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
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Academic Article
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Functional haplotypes of IL-12B are associated with childhood atopic asthma.
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Academic Article
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A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
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Academic Article
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Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
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Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
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Academic Article
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Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
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Academic Article
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Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
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Academic Article
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A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
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Academic Article
|
Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
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Academic Article
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Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
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Academic Article
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Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
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Academic Article
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Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
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Academic Article
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Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Common variants in CASP3 confer susceptibility to Kawasaki disease.
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Academic Article
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The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
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Academic Article
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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
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Academic Article
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Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
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Academic Article
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Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
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Academic Article
|
Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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Impact of four loci on serum tamsulosin hydrochloride concentration.
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Academic Article
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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
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Academic Article
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Variations in the FTO gene are associated with severe obesity in the Japanese.
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Academic Article
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C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
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Academic Article
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Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
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Academic Article
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INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
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Academic Article
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Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
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Academic Article
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Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
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Academic Article
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A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
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Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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Academic Article
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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
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Academic Article
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Impact of PSCA variation on gastric ulcer susceptibility.
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Academic Article
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Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
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Academic Article
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A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
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Academic Article
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Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
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Academic Article
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A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
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Academic Article
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Genome wide association study of age at menarche in the Japanese population.
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Academic Article
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Association of the RIP2 gene with childhood atopic asthma.
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Academic Article
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Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
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Academic Article
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ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
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Academic Article
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MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data.
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Academic Article
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Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
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Academic Article
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Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
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Academic Article
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ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
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Academic Article
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HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
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Academic Article
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A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
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Academic Article
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Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
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Academic Article
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Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
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Academic Article
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Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
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Academic Article
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Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
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Academic Article
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High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
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Academic Article
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Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
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Academic Article
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Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
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Academic Article
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Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
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Academic Article
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Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection.
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Academic Article
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Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
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Academic Article
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A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
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Academic Article
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Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
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Academic Article
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Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
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Academic Article
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Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
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Academic Article
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Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
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Academic Article
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The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
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Academic Article
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Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
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Academic Article
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Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
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Academic Article
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Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
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Academic Article
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An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
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Academic Article
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Seven new loci associated with age-related macular degeneration.
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Academic Article
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Pathway analysis of genome-wide data improves warfarin dose prediction.
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Academic Article
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Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
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Academic Article
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Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
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Academic Article
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Trans-ethnic meta-analysis of white blood cell phenotypes.
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Academic Article
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
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Academic Article
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Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
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Academic Article
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Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
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Academic Article
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A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
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Academic Article
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
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SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax.
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Academic Article
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High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24-q25.
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Academic Article
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Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
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Academic Article
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Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
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Academic Article
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Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.
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Academic Article
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Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
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Academic Article
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Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
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Academic Article
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Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
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Academic Article
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CD40 ligand gene and Kawasaki disease.
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Academic Article
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Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
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Academic Article
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Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
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Academic Article
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Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
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Academic Article
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Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
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Academic Article
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Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
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Academic Article
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
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Academic Article
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Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
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Academic Article
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Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
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Academic Article
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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
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Academic Article
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Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas.
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Academic Article
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Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
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Academic Article
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Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
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Academic Article
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906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
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Academic Article
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Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
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Academic Article
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Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
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Academic Article
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A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.
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Academic Article
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Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
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Academic Article
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Oncogenic role of NALP7 in testicular seminomas.
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Academic Article
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[SNP collection, pharmacogenomics, and the future of drug therapy].
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Academic Article
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Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
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Academic Article
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Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
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Academic Article
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A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
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Academic Article
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Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
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Academic Article
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Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
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Academic Article
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Expression profiles of two types of human knee-joint cartilage.
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Academic Article
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Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
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Academic Article
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High-density SNP map of human ITR, a gene associated with vascular remodeling.
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Academic Article
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Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
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Academic Article
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Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
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Academic Article
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Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
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A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
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Academic Article
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Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
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Academic Article
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Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
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Academic Article
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SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
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Academic Article
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Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
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Academic Article
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Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.
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Academic Article
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Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
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Academic Article
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Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
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Academic Article
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Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
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Academic Article
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Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
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Academic Article
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Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
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Academic Article
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Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
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Academic Article
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Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
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Academic Article
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Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
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Academic Article
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Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
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Academic Article
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Analysis of gene-expression profiles after gamma irradiation of normal human fibroblasts.
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Academic Article
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Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
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Academic Article
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A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
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Academic Article
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A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
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Academic Article
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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
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Academic Article
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A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
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Academic Article
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Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
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Academic Article
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hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
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Academic Article
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Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
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Academic Article
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A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
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Academic Article
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Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
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Academic Article
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ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
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Academic Article
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Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
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Academic Article
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Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
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Academic Article
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Prediction of response to imatinib by cDNA microarray analysis.
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Academic Article
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A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
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Academic Article
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Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.
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Academic Article
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Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
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Academic Article
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Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
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Academic Article
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Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
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Academic Article
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No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
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Academic Article
|
The BioBank Japan Project.
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Academic Article
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High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
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Academic Article
|
[S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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Recombination rates of genes expressed in human tissues.
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Academic Article
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Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
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Academic Article
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hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets.
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Academic Article
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Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
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Academic Article
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Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
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Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
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Academic Article
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Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
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Academic Article
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Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
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Academic Article
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HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
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Academic Article
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[BioBank Japan project].
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Academic Article
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The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
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Academic Article
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Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus.
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Academic Article
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Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
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Academic Article
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ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
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Academic Article
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A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Academic Article
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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
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Academic Article
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Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
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Academic Article
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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
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Academic Article
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Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.
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Academic Article
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The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
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Academic Article
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Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
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Academic Article
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Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
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Academic Article
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HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
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Academic Article
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A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
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Academic Article
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A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
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Academic Article
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Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
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Academic Article
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Population-genetic nature of copy number variations in the human genome.
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Academic Article
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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
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Academic Article
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Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
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Academic Article
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Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
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Academic Article
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A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
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Academic Article
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A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.
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Academic Article
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
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Academic Article
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Academic Article
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Identification of semaphorin3B as a direct target of p53.
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Academic Article
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Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
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Academic Article
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Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
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Academic Article
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Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
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Academic Article
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Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
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Academic Article
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A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
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Academic Article
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Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome.
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Academic Article
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Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.
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Academic Article
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Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
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Academic Article
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Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
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Academic Article
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Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
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Academic Article
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Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
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Academic Article
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Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
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Academic Article
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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
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Academic Article
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Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
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Academic Article
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International network of cancer genome projects.
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Academic Article
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Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
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Academic Article
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Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
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Academic Article
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Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
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Academic Article
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Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
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Academic Article
|
Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
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Academic Article
|
A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
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Academic Article
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Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
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Academic Article
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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
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Academic Article
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Identification of COX17 as a therapeutic target for non-small cell lung cancer.
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Academic Article
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Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
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Academic Article
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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
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Academic Article
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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
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Academic Article
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Isolation of p53-target genes and their functional analysis.
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Academic Article
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Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
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Academic Article
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From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
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Academic Article
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Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
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Academic Article
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Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
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Academic Article
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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
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Academic Article
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Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
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Academic Article
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Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
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Academic Article
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The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
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Academic Article
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Pharmacogenomics and drug toxicity.
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Academic Article
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Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
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Academic Article
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Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
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Academic Article
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Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
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Academic Article
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Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).
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Academic Article
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Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors.
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Academic Article
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Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor a and ß chains using next-generation sequencing (NGS).
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Academic Article
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Accurate automated clustering of two-dimensional data for single-nucleotide polymorphism genotyping by a combination of clustering methods: evaluation by large-scale real data.
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Academic Article
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WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
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Academic Article
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
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Academic Article
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Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
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Academic Article
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Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan.
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Academic Article
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Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
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Academic Article
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Overview of BioBank Japan follow-up data in 32 diseases.
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Academic Article
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Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
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Academic Article
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
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Academic Article
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Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
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Academic Article
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Combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features: genetic analysis for histogenesis.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
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Academic Article
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SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
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Academic Article
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Quantitative analysis and clonal characterization of T-cell receptor ß repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
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Academic Article
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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Academic Article
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miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
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Academic Article
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GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
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Academic Article
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Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
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Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
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Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
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Aldosterone-sensitive nucleus tractus solitarius neurons regulate sensitivity of the baroreceptor reflex in high sodium-loaded rats.
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TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.
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Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
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CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain.
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Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
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Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
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Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
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CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
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Clinicopathologic significance of protein lysine methyltransferases in cancer.
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Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
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Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
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Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
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Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
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A cross-population atlas of genetic associations for 220 human phenotypes.
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Concept
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Spatio-Temporal Analysis
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Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials.
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Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.
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